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KMID : 0350519960490010341
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Journal of Catholic Medical College
1996 Volume.49 No. 1 p.341 ~ p.350
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Comparsion of Seminal Parameters, Sperm Motility Index, Sperm Mucus Penetraction Distance in Evaluation of Sperm Fertilizing Capacity
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Abstract
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In infertility work-up, correct diagnosis of a possible male factor is critically dependent on the accurate determination of the motility characteristica of spermatozoa.
The recognition of the significance of objective cell motility determination led to the development of several measuring devices.
This investigation was performed to assess the correlation among conventional semial parameters, sperm mucus penetration distance and sperm motility index in motility evaluation.
These infertility work-up was done in 45 fertile men with normal semen analysis (fertile control group) and 135 infertile men (patient group) with at least one abnormal seminal parameters and fundamental tests of female partners for fertility
were
normal.
The conventional seminal parameters were evaluated according to the WHO standard normal using Markler counting chamber (Zygotek System, Inc., U.S.A.) and Hen's egg white was used for sperm mucus penetration test. The sperm motility index (SMI)
was
measured by an electro-optical device (United Medical Systems Incl., Santa Ana, CA.) and SMI values were used to grade the quality of given semen specimen and to classify in into ono of three categories : poor, medium or good semen quality.
@ES Results were as follows ;
@EN 1. The seminal parameters, SMI value and sperm penetration distance (SPD) in both fertile and patients groups showed significant statistical differences (P<0.01).
2. The SMI values of the fertile & patient groups were compared in each categories : poor (6.7% of fertiles vs 28.9% of patients), medium (20% vs 39.3%), and the differences were significant (P<0.01).
3. In the studies groups, semen with normal sperm mucus penetration distance (≥30mm) presented higher total sperm count, motility, viability and total functional sperm fraction than sbnormal SPD (<30mm) (P<0.01).
4. The Seminal Parameters in the three categories of the SMI values were significantly different, respectively (P<0.01)
5. In the studied groups (fertile and patient), the mean SMI valued of poor, medium and good categories in the normal abnormal SPD group showed significant difference. No case in the abnormal SPD group was in good SMI category (P<0.01). The mean
value
of the SMI in normal and abnormal SPD groups showed significant differe4nce (P<0.01).
6. Positive correlation was observed among the conventional sperm parameters, SPD and SMI values.
These results provided positive correlation between sperm count, motility, viability and total functional sperm fraction (TFSF) with SMI and SPD. This suggest that the SMI has the potential to replace the sperm mucus penetration test, as the most
reliable method in sperm function evaluation.
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KEYWORD
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